Who will benefit more from maintenance therapy of metastatic colorectal cancer?
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Who will benefit more from maintenance therapy of metastatic colorectal cancer?
Whether there is a difference in the efficacy of maintenance treatment for metastatic colorectal cancer (mCRC) between patients who achieve complete response (CR)/partial response (PR) and those with stable disease (SD) after induction treatment is controversial. PubMed, Cochrane Systematic Reviews, the Cochrane Collaboration Central Register of Controlled Clinical Trials, ClinicalTrials.gov, a...
متن کاملMaintenance therapy for metastatic colorectal cancer.
1444 www.thelancet.com/oncology Vol 16 November 2015 7 Blakely T, Shaw C, Atkinson J, Cunningham R, Sarfati D. Social inequalities or inequities in cancer incidence? Repeated census-cancer cohort studies, New Zealand 1981–1986 to 2001–2004. Cancer Causes Control 2011; 22: 1307–18. 8 Paltoo DN, Chu KC. Patterns in cancer incidence among American Indians/ Alaska Natives, United States, 1992–1999....
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Median overall survival of metastatic colorectal cancer patients treated with first- and second-line combination chemotherapy now extends to more than 20 months in some studies. Chemotherapy alone, particularly when oxaliplatin is included, may allow potentially curative resection of advanced disease. There is evidence that the addition of antibodies targeted against vascular endothelial growth...
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Maintenance therapy has become quite a hot topic for those of us working in the field of solid tumor malignancies. Our original concept of chemotherapy for solid tumors was to give a certain number of cycles and then stop treatment, or to continue treatment until an intolerable toxicity arose. Given that we now have more management tools at our disposal, and as treatments given chronically have...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23549